Whats Needed for Approval of Fixed-Dose Combination Products?
نویسندگان
چکیده
منابع مشابه
Fixed Dose Combination for TB treatment
According to the World Health Organization, a third of the world’s population is infected with tuberculosis. The disease is responsible for nearly 2 million deaths each year and over 8 million were developing active diseases. Moreover, according to WHO (2000), tuberculosis deaths are estimated to increase to 35 million between 2000-2020. The majority of tuberculosis patients worldwide are still...
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Hypertension is the leading cause of disability and cardiovascular mortality world-wide. Approximately one-third of the US adult population and over a billion people world-wide have hypertension. Despite increased awareness of hypertension and availability of many effective antihypertensive agents, only one third of patients achieve their target blood pressure (BP). All expert panels now recomm...
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Introduction: One of the main reasons for the development of the resistance in the therapy for Tuberculosis is the mono drug therapy. This may be due to the drug-drug interactions as the therapy includes combination of various drugs leading to poor bioavailability of these drugs. One such reported interaction is between Rifampicin and Isoniazid which leads to poor bioavailability of Rifampicin....
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Materials and methods 1681 HIV positive patients accessing care at Suntreso STI/HIV Clinic in Kumasi, who have been on treatment for more than 12 months and consented to participate were recruited for this cross sectional study. They were interviewed using semi-structured pre-texted questionnaire prior to the commencement of the new fixed dose combination ARVs treatment regime. Data was entered...
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Fixed dose combinations (FDCs) are combinations of two or more active drugs in a single dosage form. It is the current hot topic of deliberations in the pharmaceutical industry, drug regulatory agency, and the pharmaceutical trade. Surprisingly, it is not so among the doctors who prescribe the medicines or the patients who consume. Basically, from one point of view it increases patient complian...
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ژورنال
عنوان ژورنال: Journal of Bioequivalence & Bioavailability
سال: 2016
ISSN: 0975-0851
DOI: 10.4172/jbb.10000e71